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Welcome to Blossom Fertility & IVF Center..

Realising your dream
It is the dream of most couples to have their own children as part of their relationship. In India 1 in 6 couples will have problems conceiving.
The Blossom Fertility and IVF Centre aims to reduce the stress and hassle associated with infertility investigations and treatment, by offering a one-stop diagnostic and treatment service for infertile couples.

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Archive for March 2014

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It is the dream of most couples to have their own children as part of their relationship. Many couples are not fortunate enough to attain pregnancy. After one year of trying to conceive without the use of birth control, if a woman is unable to get pregnant, infertility is suspected. For the women aged 35 or over waiting period should not be for more than six months. Then it’s the time for the couple to seek the help of infertility doctors. Infertility or Fertility doctors are the specialists who study Reproductive endocrinology and Infertility (REI), a branch of medicine that identifies and treats infertility in both men and women.

In vitro fertilization is an option for many couples who cannot conceive through conventional therapies. IVF is an option for couples who have tried unsuccessfully to conceive or for whom other treatments have failed. IVF is an acronym for in vitro fertilization. IVF is one of several assisted reproductive techniques (ART) used to help infertile couples to conceive a child.

In vitro fertilization (IVF) is a complex series of procedures used to treat fertility or genetic problems and assist with the conception of a child. During IVF, mature eggs from women are collected (retrieved) from the ovaries and fertilized with the sperm of a men in a laboratory in the dish. Then the fertilized egg (embryo) or eggs are implanted in the uterus. One cycle of IVF takes about two weeks. IVF is the most effective form of assisted reproductive technology. The procedure can be done using your own eggs and your partner’s sperm. Or IVF may involve eggs, sperm or embryos from the known or anonymous donor. In some cases, a gestational carrier — a woman who has an embryo implanted in her uterus might be used. The carrier is called gestational surrogate mother.

Your chances of having a healthy baby using IVF depend on many factors, such as your age and the cause of infertility. In addition, IVF can be time-consuming, expensive and invasive. If more than one embryo is implanted in your uterus, IVF can result in a multiple pregnancy.

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IVF is an option for couples who have tried unsuccessfully to conceive or for whom other treatments have failed. The reasons IVF is done include – poor sperm quality and/or quantity, obstructions between the egg and sperm, ovulation problems, and sperm-egg interaction problems. These problems can prevent couples having a baby naturally, and IVF helps to solve this.

Other eligible patients are those with infertility due to a condition not responsive to conventional therapy, including one or more of the following:

  • Tubal blockage or failed tubal reversal
  • Endometriosis
  • Cervical factor
  • Pelvic adhesions
  • Male factor
  • Unexplained infertility/ failed conventional therapy
  • Genetic testing (PGD) for inheritable diseases
  • Genetic testing (PGD) for possible reasons for multiple miscarriages
  • Fertility preservation for cancer or other health conditions.
  • Previous tubal sterilization or removal.
  • Unexplained fertility

To be considered for IVF, a woman must either have a uterus capable of carrying a child, or a compassionate gestational carrier. For optimal results, the woman should not be more than twenty percent over her ideal body weight. Women between the ages of 40-43 are considered for IVF on an individual basis based on previous testing, such as FSH levels and/or responses to gonadotropin therapy.

In vitro fertilization (IVF) involves several steps — ovulation induction, egg retrieval, sperm retrieval, fertilization and embryo transfer. One cycle of IVF can take about two weeks, and more than one cycle may be required.

Cycle Monitoring/ Ovulation induction

To begin the process of IVF, the woman is given fertility drugs to stimulate egg production and control the timing of ovulation. This helps maximize the number of eggs produced, thereby increasing the chance that at least one will be fertilized, and will implant itself in the uterus. Frequent blood tests to monitor hormone levels and ultrasounds to monitor follicle development are required. Stimulation protocols may vary depending on multiple factors.

Egg Retrieval

The eggs are harvested primarily through a transvaginal ultrasound-guided procedure. The ultrasound-guided egg retrieval is performed on an outpatient basis with monitored I.V. sedation. Recovery from the sedation requires thirty minutes. The patient is discharged from the surgery center with instructions to rest for the remainder of the day.

Sperm Retrieval

Once the eggs are retrieved and the sperm sample collected, they are immediately given to the embryology laboratory for incubation. Normally IVF lab is located adjacent to the operating room. The man’s semen is specially prepared in order to select the most viable sperm. In conventional IVF, the sperm are then placed together with the eggs in an incubator for 12-18 hours to allow for fertilization.

Fertilization

In conventional IVF, the sperm are then placed together with the eggs in an incubator for 12-18 hours to allow for fertilization. When sperm quality is compromised, the eggs are inseminated with a single sperm by means of a micromanipulation procedure known as ICSI (intracytoplasmic sperm injection). This may also be used on half of the eggs to enhance fertilization in some circumstances. Following normal fertilization, early embryonic development is closely observed on a daily basis. In certain situations, your doctor may recommend other procedures like assisted hatching and Preimplantation genetic testing before embryo implantation.

Embryo Transfer

Within 72 hours after egg retrieval, the embryos are generally ready to be transferred into the woman’s uterus through a thin tube, or catheter, gently inserted through the cervix. This is a non-surgical procedure performed under ultrasound guidance with no need of sedation. The woman may wish to rest for the remainder of the day in order to maximize the chance for success. One should avoid vigorous activity which could cause discomfort. About ten to twelve days following the embryo transfer, the woman’s blood is drawn and tested to determine if pregnancy has occurred.

Side effects of the IVF procedure may include passing a small amount of clear or bloody fluid shortly after the procedure, Breast tenderness due to high estrogen levels, Mild bloating, Mild cramping and Constipation.IVF requires a significant physical, emotional, financial, and time commitment. The risk factors associated with IVF includes multiple births, premature delivery and low birth weight, ovarian hyperstimulation syndrome, miscarriage, egg-retrieval procedure complications, ectopic pregnancy, birth defects, ovarian cancer and stress.

Talk with our doctors about any factors that apply to you and how they may affect your chances of a successful pregnancy. Conceiving a baby seems like it should be the easiest thing in the world–but for many couples this is not the case. The decision to pursue fertility treatment is never easy. That is why you need a fertility center with the proven ability to succeed – a trusted partner that delivers results to thousands of patients every year. The Blossom Fertility and IVF Centre aims to reduce the stress and hassle associated with infertility investigations and treatment, by offering a one-stop diagnostic and treatment service for infertile couples. Infertility doctors at Blossom has a reputation for success, both in quality of care and in pregnancy and live birth rates. The fertility specialist at Blossom are committed to offer to the patients clinical excellence, cost-effective treatment options, personalized compassionate care, and exceptional success rate.

Contact us today for Best infertility treatments like IVF, ICSI, IUI, IMSI, Surrogacy in Surat at http://www.blossomivfindia.com  or at http://www.blossomivfindia.com/ivf  and gather all information to attain happy parenthood.

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One of the most frustrating aspects of assisted reproductive technology for patients and fertility professionals alike is having to deal with failure in fertility treatment. This is especially true in couples who have attempted assisted reproductive procedures many times, and also in those whose time is running out because of their age. Now, a recently developed technique, assisted hatching, is offering new hope to the couples who fall into these categories.

Assisted hatching is a laboratory technique used with IVF. It involves the use of laser to thin the outer shell (zone pellucida) of the fertilized egg, before the embryo is transferred into the uterus. Assisted hatching is used to enhance the embryos ability to hatch, and also implant, after transfer. The procedure is based on the fact that an alteration in zona pellucida (outer covering of egg) either by drilling a hole through it or by thinning it, will promote hatching or implantation of embryos that are otherwise unable to escape intact from the zona pellucida.

After a fertilized egg is returned to the uterus, several things must happen:

  1. It must continue to divide and grow (it is now called an embryo).
  2. The embryo must break out of the zona pellucida (usually called the zona) which is a hard protein shell that surrounds it.
  3. The embryo must then burrow into the lining of the uterus (called the endometrium) and continue to grow there.

It has been suggested that making a hole in or thinning this outer layer may help embryos to ‘hatch’, increasing the chances of the woman becoming pregnant in some cases. Assisted hatching is indicated for infertile couples in following cases.

  1. when the zona pellucida is noted to be excessively thick when measured on a day 3 embryo by the embryologist
  2. with poor embryo quality
  3. In women with an elevated Day 3 FSH
  4. when a Flare stimulation protocol has been used
  5. when the female partner age is 38 or older at the time of stimulation, or
  6. with previous IVF implantation failure of embryos to implant though results were otherwise good
  7. Frozen embryo replacements.

Laser Assisted Embryo Hatching

Laser Assisted Embryo Hatching

How does the procedure of Assisted Hatching work?

Assisted hatching is carried out in the laboratory by experienced embryologists. The assisted hatching procedure, like ICSI, is carried out by a technique known as micromanipulation. In small dishes the embryos, which now contain an average of six to eight cells, are stabilized by a holding pipette, while on the opposite side a small pipette containing acidified Tyrode’s solution creates a small defect in the zona. Just before the embryos are replaced, whether they are fresh or frozen/thawed, a small hole is made in the zona, or by thinning it using a micromanipulation technique. The process is repeated for each embryo. The main methods currently in use for assisted hatching are: chemical, mechanical and laser. The process will damage about 1% of embryos.

Most IVF clinics will not perform assisted hatching if there is one embryo available because of possible damage to this embryo would result in no embryo transfer. The assisted hatched embryos are then transferred into the uterine cavity as usual. Some clinics will give the woman a course of antibiotics to prevent infection. (Assisted hatching deprives the embryo of its intact protective coat, which shields it from exposure to any harmful factors in the uterus).

Assisted Hatching using laser technology is probably the best technique. Laser assisted hatching is a gentle and safe way to weaken a part of zona pellucida. Several studies have shown that using a laser is superior to chemical and manual hatching. Minimal handling of the embryo and delivering fast and exact control over the drilling of the hole are the advantages of laser assisted hatching.

Advantages of using Assisted Hatching

This relatively small variation in the IVF procedure has yielded dramatic results in older patients and those with previously failed cycles.

1) It provides “mechanical advantage” to the embryos in breaking the zona for implantation.

2) It also ensures early contact of embryos with endometrium. This expedites enzymetic reaction between endometrium and embryos called “Embryo endometrium cross talk”.

3) Mechanical advantages and chemical advantage ensure better implantation rate and better pregnancy rate.

4) It helps women with previous failed IVF cycle.

Disadvantages

The addition of assisted hatching to the standard IVF protocol does add extra laboratory manipulation and therefore added costs. There is a small risk of damage to the embryo during the micromanipulation process or at the time of transfer, and there is a slight increase in identical twinning. There is a greater chance of fetal complications and abnormalities in some identical twins. A rare complication of identical twinning is conjoined or “Siamese” twins. No higher rate of identical twins is observed than with routine IVF. This may relate to whether a large enough opening is made in the zona to prevent pinching of the embryo during the hatching process.

Assisted hatching of IVF embryos, is an Assisted Reproductive Technology procedure which is performed in IVF laboratory. It increases IVF success rates. Consult infertility expert at Blossom Fertility centre in Surat for complete medical advice for infertile couples.

At the Blossom Fertility and IVF Centre Surat, Laser Assisted Hatching technique is used to perform the assisted hatching procedure.Doctors and embryologist are well conversant with the latest technology in the field of ART (Assisted Reproductive Technology). You can contact the top IVF doctors, Fertility specialist Surat and embryologist in surat at Blossomivfindia.com or at IVFfertility-treatments

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